Hidradenitis

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hidradenitis

[‚hī‚drad·ən′īd·əs]
(medicine)
Inflammation of sweat glands.

Hidradenitis

 

a suppurative inflammation of the sweat glands. It is caused by staphylococcus and usually develops in the armpits, but it is seen more rarely around the nipples, sexual organs (in females), and the skin of the scrotum and anus.

A weakening of the organism, excessive perspiration, intertrigo, and poor personal hygiene are all predisposing factors of this disease. Hidradenitis begins with the inflammation of the sweat gland, which spreads to the surrounding subcutaneous adipose tissue. One or several dense diseased nodules appear deep in the skin, and the skin above them reddens. Then the nodules soften and open with the formation of purulent fistulous passages. The pus gets into the neighboring glands and infects them. The course of hidradenitis is long, often with relapses. Women are affected more often than men. Treatment of hidradenitis calls for antibiotics, physiotherapy, specific vaccinations, unspecific immunotherapy, and sometimes surgery.

REFERENCE

Mnogotomnoe rukovodstvo po dermato-venerologii, vol. 2. Edited by S. T. Pavlov. Leningrad, 1961.
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The open IND will allow InflaRx to conduct a phase IIb study to determine efficacy and safety of IFX-1, a first-in-class anti-human complement factor C5a antibody, in patients with moderate or severe Hidradenitis Suppurativa (HS), a painful, chronic, and debilitating inflammatory skin disease.
We describe a simple option- keystone design, islanded, perforator flap from the adjacent area for the cover of axillary defect after wide local excision of scarred, infected skin affected by hidradenitis suppurativa of axilla.
When treating hidradenitis suppurativa, it is imperative to not only treat the skin but also to look for associated comorbidities," Maria del Carmen Liy-Wong, MD, said in an interview in advance of the World Congress of Pediatric Dermatology.
The characterization of pediatric HS in the literature needs to be improved so that adult style therapeutics can begin to be applied in pediatric clinical trials, she said at a hidradenitis suppurativa symposium at George Washington University in Washington.
Patients with branching fistulous tracts, multiple fistulae, malignant fistula, inflammatory bowel disease (IBD), tuberculosis, hidradenitis suppurativa, HIV, diabetes mellitus, using steroids and recurrent fistula were excluded from the study.
It is unclear what other indications Boehringer may seek for its adalimumab biosimilar, but Amjevita is indicated for several forms of arthritis, psoriasis, pediatric plaque psoriasis, hidradenitis suppurativa, Crohn's disease, ulcerative colitis and uveitis.
It is a member of the follicular occlusion tetrad, which also includes hidradenitis suppurativa, acne conglobata, and dissecting cellulitis of the scalp (2).
Background: Acne inversa (AI), also called hidradenitis suppurativa, is a chronic, inflammatory, recurrent skin disease of the hair follicle.
11 Serum YKL-40 levels have been investigated in different inflammatory dermatological diseases such as psoriasis, psoriatic arthritis, hidradenitis suppurativa.
org, the website for healthcare professionals, has recently announced the addition of a new clinical resource on hidradenitis suppurativa (HS), also known as acne inversa.
GlobalData's clinical trial report, "Hidradenitis Suppurativa Global Clinical Trials Review, H1, 2016" provides an overview of Hidradenitis Suppurativa clinical trials scenario.
Increased eccrine gland function leads to miliaria, hyperhidrosis, dyshidrotic eczema, and decreased apocrine gland function leads to improvement in hidradenitis suppurativa, Fox- Fordyce disease.