lesion

(redirected from high-grade squamous intraepithelial lesion)
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Related to high-grade squamous intraepithelial lesion: HSIL

lesion

any structural change in a bodily part resulting from injury or disease

lesion

[′lē·zhən]
(biology)
A structural or functional alteration due to injury or disease.
(cell and molecular biology)
A damaged site in a gene, chromosome, or protein molecule.
References in periodicals archive ?
The significance of the Papanicolaou smear diagnosis of low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion.
The ASCUS result persisted in 5 (3%), progressed to low-grade squamous intraepithelial lesions (LSIL) in 11 (8%), and progressed to high-grade squamous intraepithelial lesions (HSIL) in 7 (5%).
High-grade squamous intraepithelial lesion was the third most-common Pap test result, following ASC-US and ASC-H.
Papanicolaou tests were evaluated using the current (2001) Bethesda classification system, with the addition of the category of low-grade squamous intraepithelial lesion, a high-grade squamous intraepithelial lesion cannot be ruled out (LSIL-H).
Yes, regularly: 88% No, not at all: 1% Only as part of scheduled employee reviews: 11% Abbreviations: ACG, atypical glandular cells; ASC-H, atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial lesion.
1-9) High-grade squamous intraepithelial lesion is known to recur after LEEP procedures, with margin status being the most important predictor of subsequent occurrence of HSIL.
15) These recommendations include referral based on low-grade squamous intraepithelial lesion (LSIL) or high-grade squamous intraepithelial lesion (HSIL) cytology or an atypical squamous cell of undetermined significance (ASCUS) cytology and an HPV DNA positive reflex test.
6%) were interpreted as squamous cell abnormalities according to the Bethesda System 2001 (TBS 2001) classification, including 1125 cases (85%) of atypical squamous cells of undetermined significance; 36 cases (3%) of atypical squamous cells, for which a high-grade squamous intraepithelial lesion could not be excluded; 148 cases (11.
12) Early data from Australia, where high penetrance of the vaccine has already occurred in school-aged girls, shows that, in the vaccinated population, decreases in high-grade squamous intraepithelial lesion are already occurring, when compared with nonvaccinated cohorts.
Colposcopy has a mean 90% specificity for diagnosis of HPV-related high-grade squamous intraepithelial lesions (HSIL) or cervical cancer, while high-resolution anoscopy as a diagnostic test has a specificity as low as 37% in HIV-positive persons.