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Hippuric Acid |
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hippuric acid [hi′pyu̇r·ik ′as·əd]
(organic chemistry) C6H5CONHCH2·COOH Colorless crystals melting at 188°C; soluble in hot water, alcohol, and ether; used in medicine and as a chemical intermediate. Hippuric Acid benzoylglycine, C6H5CONHCH2COOH, a compound consisting of benzoic acid and glycine groups; colorless, crystalline; melting point, 187.5° C. Hippuric acid is formed in most animals and in man, primarily in the liver, and passes out in the urine. The biological significance of hippuric acid synthesis in the body is in the binding of benzoic acid, which is liberated during the destruction of the aromatic compounds that are a part of the makeup of plant tissues. In clinical practice the liver’s detoxication ability is measured by a test for hippuric acid synthesis (Quick’s test). Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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No references found | Cranberry juice and the antibacterial action of hippuric acid. [ILLUSTRATION OMITTED] In the 1840s German scientists researched the connection between cranberries and urinary tract infections (UTIs) after noting that urinary excretion of hippuric acid increased after ingestion of cranberries, which are bacteriostatic in high concentrations (Hutchinson 2005, Ulbricht 2005, Siciliano 1996). The further analysis of cranberry metabolites showed that the urine from Group III participants contained significantly higher levels of hippuric acid, conjugates of some other phenolic acids and quercetin glucuronide, but otherwise showed no significant increase in acidity. |
Hippuric Acid |
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