histiocyte


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Related to histiocyte: Langerhans cell

histiocyte

[′his·tē·ə‚sīt]
(histology)
References in periodicals archive ?
Erdheim-Chester disease and Langerhans Cell Histiocytosis are histiocytic diseases involving the excessive production of histiocytes, a type of white blood cell.
Mechanisms involved and differential diagnoses of typical clinical and laboratory findings in HLH * Pathology Mechanism Cytopenia/s Haemophagocytosis via activated histiocytes Liver dysfunction Infiltration by activated histiocytes Hepatocyte damage Fever Pro-inflammatory cytokine release by CTL/NK cells Neurological Demyelination deficit/s Hyperferritinaemia Released from activated histiocytes ?
Hemophagocytic syndrome (HPS) is a hematological phenomenon characterized by the activation of either macrophages or histiocytes that contain prominent hemophagocytosis features in the bone marrow and other reticulo-endothelial systems.
From this case study and others, we may conclude that apo E3[DELTA]149Leu causes a lipid-storage disease characterized by splenomegaly, splenic infiltration with foamy and sea-blue histiocytes, and hypertriglyceridemia that may be unmasked following splenectomy.
Morphologically, the tumour pattern, as seen in other subtypes, is composed of a mixture of fibroblasts, histiocytes and osteoclast-type giant cells in relatively changing amounts.
Microscopically, histiocytes were abundant in the maternal space (chronic intervillositis) and were noted within the fetal chorionic villi (Hofbauer cells; Figure 1, panel A).
Sea-blue histiocyte syndrome in bone marrow secondary to total parenteral nutrition including fat-emulsion sources: a clinicopathologic study of seven cases.
Histopathologically, the dermal lesion contained a mixture of histiocytes, foamy macrophages, lymphocytes, and scattered Touton giant cells (figure 2).
Upper) Peripheral blood smear showing suspicious histiocyte engulfing blood cells; (Lower) Bone marrow smear showing hemophagocytic process with histiocyte phagocytosing leukocyte and erythrocytes.