histiocytoma


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histiocytoma

[‚his·tē·ō‚sī′tō·mə]
(medicine)
Benign tumor composed of histiocytes.
Dermatofibroma.
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The differential diagnosis is fairly broad and includes phlegmon/abscess, nerve sheath tumor, synovial sarcoma, fibrous histiocytoma (benign, malignant and angiomatoid forms), angiosarcoma, and fibromatosis.
This tumor's differential diagnoses include adenomyoepithelioma, phyllodes tumor, adenoleiomyoma, fibroadenoma with prominent smooth muscle, fibromatosis, benign spindle cell tumor of the breast, fibrous histiocytoma, myoid hamartoma, myoepithelioma, fibromato-sis-like low-grade metaplastic carcinoma and leiomyosarcoma of the breast (9).
The differential diagnosis of retroperitoneal schwannoma includes paraganglioma, neurofibroma, ganglioneuroma, tumors of mesodermal origin and retroperitoneal malignancies (malignant fibrous histiocytoma, lymphoma and liposarcoma) (3).
Cytologic atypia, giant cells in the fibrohistiocytic type and an appearance of a prominent storiform pattern with an SFT may bring malignant fibrous histiocytoma to mind.
Other differential diagnoses include leiomyosarcoma, fibrosarcoma, rhabdomyosarcoma, malignant fibrous histiocytoma, spindle cell melanoma and metastatic transitional cell carcinoma.
Figures 1-3 are depicting microscopic pictures of teratocarcinoma, seminoma and malignant fibrous histiocytoma.
4) It is one of the most difficult lesions to diagnose because it can be confused with spindle cell sarcoma, fibromatosis, fibrous histiocytoma, nerve sheath tumors, and pleomorphic adenomas.
Malignant changes with fibrous dysplasia include Osteosarcoma, Fibrosarcoma, Chondrosarcoma, Malignant fibrous histiocytoma and Ewings sarcoma.
As the structures where the tumors originate are diverse, there are various types of soft tissue sarcoma, and the most common types include leiomyosarcoma, liposarcoma and malignant fibrous histiocytoma.
The permanent section was positive for CD68, and it yielded a final diagnosis of a high-grade sarcoma consistent with a malignant fibrous histiocytoma with giant cells.
The neoplasms commonly associated with external ear include ceruminal gland or sebaceous adenoma or adenocarcinoma, papilloma, ceruminal gland carcinoma, histiocytoma, mast cell tumor, basal cell carcinoma, malignant melanoma and squamous cell carcinoma (Slatter, 2003).
Sarcomatous de- differentiation (osteosarcoma, fibrosarcoma, malignant fibrous histiocytoma or rarely chondrosarcoma) is occasionally seen (<1%) and is more common in the polyostotic form8.