holoenzyme


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Related to holoenzyme: apoenzyme

holoenzyme

[¦häl·ō′en‚zīm]
(biochemistry)
A complex, fully active enzyme, containing an apoenzyme and a coenzyme.
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References in periodicals archive ?
Interestingly, Fur efficiently represses transcr- iption even if RNA polymerase holoenzyme (RNAP) is incubated with the dhb promoter region before the addition of Fur.
OxyFMN and holoenzyme share an open conformation with a lifetime of 4.
These data suggest that the C subunit serves as a substrate for protein kinase A and that its phosphorylation may be the main mechanism underlying the formation of the active V1V0 holoenzyme (Voss et al.
28) Recently, the crystal structure of the pol [gamma] holoenzyme was solved.
The V-ATPase holoenzyme contains 3 copies of subunit A and B, 6 copies of subunit c and one copy each of all other subunits [5,49-50].
These include recently developed methods having widespread application, such as targeting the telomerase holoenzyme, its RNA template, and other elements associated with telomerase activity.
Methods employing recombinant glycosylated holoenzyme as the antigen with high degree of purity and consistency provide more reliability in the detection of intrinsic factor antibodies.
Trewhella, Quaternary Structures of a Catalytic Subunit-Regulatory Subunit Dimeric Complex and the Holoenzyme of the cAMP-Dependent Protein Kinase by Neutron Contrast Variation, J.
Supporting that notion, Scully and his colleagues report in the May 27 Proceedings of the National Academy of Sciences that BRCA1 may be part of RNA polymerase II holoenzyme, a large collection of proteins used to create strands of RNA, the first step in assembling a gene's protein.
Chronic treatment with azide in situ leads to an irreversible loss of cytochrome c oxidase activity via holoenzyme dissociation," The Journal of Biological Chemistry, vol.