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homeobox |
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homeobox [′hō·mē·ə‚bäks] (cell and molecular biology) A highly conserved sequence of deoxyribonucleic acid (DNA) that occurs in the coding region of development-controlling regulatory genes and codes for a protein domain that is similar in structure to certain DNA-binding proteins and is thought to be involved in the control of gene expression during morphogenesis and development. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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In contrast, a sequence with low identity to a novel homeobox gene ANF-1 and a second a transcript with similarities to a human brain dynein [beta] chain, the KIAA0944 protein, both appeared to be downregulated by [E. Homeobox genes control the general shape of the fetal body. For example, in species ranging from humans to mice to fruit flies, the homeobox genes, a collection of genes that guides the development of the embryo by turning on other genes, help distinguish the animal's eventual head from its tail--and all points in between. |
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