homeobox

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Related to homeobox gene: Hox gene

homeobox

[′hō·mē·ə‚bäks]
(cell and molecular biology)
A highly conserved sequence of deoxyribonucleic acid (DNA) that occurs in the coding region of development-controlling regulatory genes and codes for a protein domain that is similar in structure to certain DNA-binding proteins and is thought to be involved in the control of gene expression during morphogenesis and development.
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References in periodicals archive ?
Isolation of Dlx and Emx gene cognates in an agnathan species, Lampetra japonica, and their expression patterns during embryonic and larval development: conserved and diversified regulatory patterns of homeobox genes in vertebrate head evolution.
Control of neural development and function in a thermoregulatory network by the LIM homeobox gene lin-11.
Two other homeobox genes known to play a role in head development in both arthropods and vertebrates have been characterized.
We further propose that LIM homeobox gene function in neural development represents a function of these genes that has been conserved across phylogeny.
Differential activation of Xenopus homeobox genes by mesoderm-inducing growth factors and retinoic acid.
Life stage and tissue-specific expression of the homeobox gene cnox1-Pc of the hydrozoan Podocoryne carnea.
Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development.
The NK homeobox gene cluster (NK cluster) is probably the most ancient homeobox gene duster, dating at least from the base of the Bilateria.
A homeobox gene, HLXB9, is the major locus for dominantly inherited sacral agenesis," Nature Genetics, vol.
In addition to these, one important mediator is the homeobox gene pitx2, which expressed asymmetrically in the left lateral plate mesoderm (LPM), tubular heart and early gut tube (Campione et al.
The intestinal CDX2 homeobox gene is a target of PTEN/phosphatidylinositol 3-kinase signaling and tumor necrosis factor a signaling via Nuclear Factor ?
As a proof of principle, they used the CRISPR-Cas9 technology to disrupt the coding sequence of the homeobox gene, Evx1 in mouse embryonic stem cells.