In cases in which homozygotes
are difficult to distinguish, amplicon-melting analysis can still provide complete genotyping information via their mixing with a known homozygote
followed by quantitative heteroduplex analysis (13).
neither Cys282Tyr homozygotes
nor Cys282Tyr/His63Asp compound heterozygotes).
07[degrees]C after temperature correction, allowing good separation of both homozygotes
in all assays.
of Patients Global distribution Homozygote
Heterozygote Exon 10 1 6 Global Exon 10 -- 1 Germany-Iran Exon17a -- 1 Iran Table 3.
Those with MT1A (rs8052394) heterozygote GA and homozygote
variant GG genotypes had lower hair mercury levels than did those with homozygote
AA genotype (Table 5; see Supplemental Material, Figure 1d).
People with the Trp460 allele has a lowered BP to greater levels in response to diuretic therapy and are more responsive to sodium challenges (25) compared with [alpha]-adducin Gly460Gly homozygotes
11) Mean 24 h intragastric pH measured at intervals of 2 h in healthy Japanese normal homozygotes
, heterozygotes and mutant homozygotes
Control DNAs from HFE normal individuals, C282Y and H63D heterozygotes, and C282Y homozygotes
also produced the expected band patterns (data not shown).
There wasn't a significant difference in occurrence of vascular events between the patients that were carrying the ACE D/D homozygous allele to ACE I/D heterozygoues, and I/I homozygote
allele carriers (P = 0.
For instance, if any of two polymorphisms, homozygote
or heterozygote, is detected in a woman, the OR for the increased risk of RPL will be calculated by multiplying the OR of the individual genes.
It was suggested that M694V homozygote
mutation may have a tendency for inadequacy of colchicine therapy.
Because of the small numbers in both H63D and C282Y homozygotes
groups, our study population was further merged into two categories indicating the presence of any H63D or C282Y allele.