homozygote


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homozygote

(hō'mōzī`gōt): see geneticsgenetics,
scientific study of the mechanism of heredity. While Gregor Mendel first presented his findings on the statistical laws governing the transmission of certain traits from generation to generation in 1856, it was not until the discovery and detailed study of the
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.

Homozygote

 

a cell or an organism in whose genetic makeup the homologous chromosomes carry the identical form of a given gene. A homozygote originates during the fusion of gametes that are identical for a given gene. The genetic formula of a diploid organism homozygous for allele A or a can be written in the form AA or aa; for a triploid organism, AAA or aaa; and so forth.

homozygote

[¦hō·mə′zī‚gōt]
(genetics)
An individual who has identical alleles at one or more loci and therefore produces identical gametes with respect to these loci.
References in periodicals archive ?
6 OR: odds ratio; CI: confidence interval; Codominant model 1: heterozygote vs wild homozygote; Codominant model 2: mutational homozygote vs wild homozygote.
The aim of the current study is to isolate homozygous [alpha]GT KO cells from postnatal heterozygous [alpha]GT KO skin fibroblasts and ultimately to evaluate the developmental competence of isolated homozygote cells after SCNT.
7] The potential risk factors for thrombosis in our case were thrombocytosis, hypoalbuminemia, hyperlipidemia and long-term steroid use owing to NS as well as the presence of MTHFR A1298C homozygote mutation.
Occurrence of the GSTP1 Val/Val homozygote was found to be more frequent in the control group than the asthmatics in a study carried out on Tunisian Children, moreover there was a higher prevalence of GSTP1 Ile allele in the asthmatic children than the control group (43.
Furthermore, as presented above, consanguineous marriages within families that carry familial translocations can result in formation of homozygotes for Robertsonian translocations.
Compared with the MT1M (rs2270836) homozygote genotype GG, subjects with homozygote variant genotype AA had lower urinary mercury levels [Table 4; sec Supplemental Material, Figure la, b (http://dx.
Of these, 6 were heterozygote for H63D and one was homozygote for H63D.
Patients were classified according to their [alpha]-adducin gene polymorphisms; Gly460Gly homozygotes--Group 1 (n=28) and Trp460Trp homozygotes and Gly460Trp heterozygotes--Group 2 (n=21).
In contrast, normal homozygote EMs (CYP2C19*1/*1 ) have both the normal alleles and heterozygote EMs have one normal allele that leads to the synthesis of active CYP2C19 enzyme leading to efficient metabolism of OPZ to 5-OH-OPZ.
Compound heterozygotes involving HbS generally experience symptoms intermediate between a sickle cell homozygote (SS) and the asymptomatic heterozygote (AS).