homozygote


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homozygote

(hō'mōzī`gōt): see geneticsgenetics,
scientific study of the mechanism of heredity. While Gregor Mendel first presented his findings on the statistical laws governing the transmission of certain traits from generation to generation in 1856, it was not until the discovery and detailed study of the
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.

Homozygote

 

a cell or an organism in whose genetic makeup the homologous chromosomes carry the identical form of a given gene. A homozygote originates during the fusion of gametes that are identical for a given gene. The genetic formula of a diploid organism homozygous for allele A or a can be written in the form AA or aa; for a triploid organism, AAA or aaa; and so forth.

homozygote

[¦hō·mə′zī‚gōt]
(genetics)
An individual who has identical alleles at one or more loci and therefore produces identical gametes with respect to these loci.
References in periodicals archive ?
In cases in which homozygotes are difficult to distinguish, amplicon-melting analysis can still provide complete genotyping information via their mixing with a known homozygote followed by quantitative heteroduplex analysis (13).
neither Cys282Tyr homozygotes nor Cys282Tyr/His63Asp compound heterozygotes).
07[degrees]C after temperature correction, allowing good separation of both homozygotes in all assays.
of Patients Global distribution Homozygote Heterozygote Exon 10 1 6 Global Exon 10 -- 1 Germany-Iran Exon17a -- 1 Iran Table 3.
Those with MT1A (rs8052394) heterozygote GA and homozygote variant GG genotypes had lower hair mercury levels than did those with homozygote AA genotype (Table 5; see Supplemental Material, Figure 1d).
People with the Trp460 allele has a lowered BP to greater levels in response to diuretic therapy and are more responsive to sodium challenges (25) compared with [alpha]-adducin Gly460Gly homozygotes.
11) Mean 24 h intragastric pH measured at intervals of 2 h in healthy Japanese normal homozygotes, heterozygotes and mutant homozygotes was 2.
Control DNAs from HFE normal individuals, C282Y and H63D heterozygotes, and C282Y homozygotes also produced the expected band patterns (data not shown).
There wasn't a significant difference in occurrence of vascular events between the patients that were carrying the ACE D/D homozygous allele to ACE I/D heterozygoues, and I/I homozygote allele carriers (P = 0.
For instance, if any of two polymorphisms, homozygote or heterozygote, is detected in a woman, the OR for the increased risk of RPL will be calculated by multiplying the OR of the individual genes.
It was suggested that M694V homozygote mutation may have a tendency for inadequacy of colchicine therapy.
Because of the small numbers in both H63D and C282Y homozygotes groups, our study population was further merged into two categories indicating the presence of any H63D or C282Y allele.