homozygous


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homozygous

Genetics (of an organism) having identical alleles for any one gene

homozygous

[‚hō·mə′zī·gəs]
(genetics)
Of or pertaining to a homozygote.
References in periodicals archive ?
Patients presenting with equivocal results may prove problematic in differentiating a diagnosis of homozygous Hb E from one of compound heterozygosity for Hb E and ?
Constructing a bank of homozygous lines will be difficult, not only because of the numerous ethical and political challenges we address later in this paper.
When a gene is dominant, a single copy in a heterozygous plant will confer the desirable trait, making the plant visually indistinguishable from the true-breeding, homozygous plant.
Studies in healthy Caucasian Europeans and North Americans show that approximately 1% of the population are homozygous for this deletion (D32), whereas 15% to 20% are heterozygous (5-t)); surprisingly, a higher percentage (up to 20%) of persons at high risk for HIV but HIV-negative are homozygous for this deletion.
The first group is the approximately 50% of patients with the beta-1 389 arginine homozygous genotype, who had an enhanced response (event rate reduction by 74%); the next group is the approximately 40% of patients with a second genotype (beta-1 389 glycine carriers + alpha-2C 322-325 wild type homozygous) who had an intermediate response (event rate reduction by 49%) to Gencaro; and the remaining group is the approximately 10% of patients with a third genotype (beta-1 389 glycine carriers + alpha-2C 322-325 Deletion carriers), that had no response.
Starting with the largest public cord blood repository in the nation, the Milstein National Cord Blood Center has more of the very rare homozygous stem cell units than any other institution.
However, both homozygous and heterozygous APOE epsilon-4 carriers had more test-specific distress than did carriers of other APOE alleles, noted coauthor Leo B.
He said that the results were quite different in the control group following the low fat control diet, where homozygous carriers were almost three times as likely to have a stroke compared to people with one or no copies of the gene variant.
Certain methodologies allow the operator to determine if a hemoglobin variant is homozygous (i.
In homozygous [alpha]-thalassemia, deletion of both copies of each of the 2 [alpha]-globin genes on chromosome 16 occurs, and thus no [alpha]-globin is produced.
The frequency of mutant alleles in the positive cases was found to be in accordance with the homozygous wild (HW) equilibrium and in negatives it was not determined as there was no mutation in the gene.