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human leukocyte antigen

   Also found in: Dictionary/thesaurus, Medical, Legal, Acronyms, Wikipedia, Hutchinson 0.06 sec.
human leukocyte antigen [¦yü·mən ¦lü·kə‚sīt ′ant·i·jən]
(immunology)
Any of a group of antigens present on the surface of nucleated body cells that are coded for by the major histocompatibility complex of humans and thus allow the immune system to distinguish self and nonself. Abbreviated HLA.


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Treatment with inhaled corticosteroids reduces expression of activation markers CD25 and human leukocyte antigen (HLA)-DR in lung lymphocytes and also reduces HLA-DR expression in blood lymphocytes (Wilson et al.
The testing method, called human leukocyte antigen typing, was eventually deregulated and the process was commercialized.
HLA: human leukocyte antigens, which are marker molecules on the surface of cells that identify cells as "self" and prevent the immune system from attacking them.
 
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