hyaline cast


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hyaline cast

[′hī·ə·lən ¦kast]
(pathology)
A clear, structureless mass of proteinaceous material found in the urine in association with certain kidney diseases.
References in periodicals archive ?
It provides quantitation of erythrocytes and leukocytes, semi-quantitative assessment of bacteria, epithelial cells, and hyaline casts, and qualitative evaluation of pathologic casts, crystals, yeast, sperm, and mucus.
leukocyturia, hematuria, granular casts, hyaline casts, * Predominantly segmental red blood cell casts, fatty proliferation, necrosis casts, oval fat bodies) * Predominantly mesangial and subendothelial immune deposits Variable but usually nonnephrotic proteinuria Class IV.
Approximately 500 images per sample are collected as the software classifies particles into categories including RBC, WBC, WBC clumps, hyaline casts, pathological casts, squamous epithelial cells, non-squamous epithelial cells, bacteria, yeast, crystals, mucus, and sperm.
The presence of pathologic casts or other particles was not confirmed in one-half of the cases because high numbers of hyaline casts, ECs, and cell debris also can cause such flags.
The analyzer classifies images into categories including RBC, WBC, WBC clumps, hyaline casts, unclassified casts, EC, nonsquamous EC, bacteria, yeast, crystals, mucus, sperm, and amorphous substances.
Quantitative counts were obtained for bacteria (BACT channel, counting particles with diameter [greater than or equal to] 2 [micro]m), RBCs, white blood cells (WBCs), casts (CAST channel; gated to detect mainly inclusion-bearing granular or cellular casts because hyaline casts are difficult to discern from slime threads with such an analyzer), large epithelial cells (ECs), and small round cells (SRCs; including both epithelial and inflammatory cells).
The new system analyzes 4 mL of urine in an automated mode and 1 mL of urine in a manual mode, and aspirates 1,200 uL (automated mode) and 800 uL (manual mode) for microscopic scrutiny, using two channels, one for bacteria detection and one for the enumeration of RBC, WBC, epithelial cells, hyaline casts, and the flagging parameters.