hybridoma


Also found in: Dictionary, Thesaurus, Medical, Wikipedia.

hybridoma

[‚hī·brə′dō·mə]
(immunology)
A hybrid myeloma formed by fusing myeloma cells with lymphocytes that produce a specific antibody; the individual cells can be cloned, and each clone produces large amounts of identical (monoclonal) antibody.
References in periodicals archive ?
The AM 2 IgG is 12-fold improved relative to the starting hybridoma, with a [K.
Because individual hybridomas are cultured, crude preparations can be used to elicit immune responses, but the cell lines that demonstrate affinity to the immunogen must be screened for specificity post-culture.
Mouse serum titrations and screening of hybridoma supernatants were performed by Enzyme-linked immunosorbent assay (ELISA).
The fused hybridoma cells were propagated in RPMI 1640 supplemented with 100 mL/L fetal bovine serum, hypoxanthine, aminopterin, and thymidine.
In the laboratory flasks, these hardworking hybridomas become tiny factories, churning out antibodies.
Microscopic examination of joint tissue supported the findings that arthritic mice were helped by hybridoma treatment, says Kresina.
Starting from a hybridoma cell line, Creative Biolabs offers the following services:
30 April 2010 - Norwegian cancer drug development company Clavis Pharma ASA (OSL: CLAVIS) said today that it has inked a licence agreement with Ventana Medical Systems Inc, a wholly owned member of the Roche Group (VTX: ROG), providing Ventana with exclusive access to Clavis Pharma's monoclonal antibody targeting human nucleoside transporter 1 (hENT1) and to the hybridoma cell line that produces the antibody.
In the present study, we constructed a scFv, using mRNA from the well-characterized anti-CEA hybridoma cell line T84.
is working to accelerate the development of an autologous vaccine for non-Hodgkins lymphoma produced from a hybridoma using the Biovest proprietary bioreactor.