hydralazine


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Related to hydralazine: labetalol

hydralazine

[hī′dral·ə‚zēn]
(pharmacology)
C8H8N4 An antihypertensive drug; used as the hydrochloride salt.
References in periodicals archive ?
The primary objective of this study was to compare the effects of labetalol, nicardipine, and hydralazine on time to target blood pressure before alteplase administration in patients with acute ischemic stroke.
The effect of some parameters on the test, such as time, temperature, buffer and the amount of stabilizer, has been also investigated in this method," stated Hatami and that "this method has been used to measure the Hydralazine composition in medicines available on the market, and has provided acceptable results.
Hydralazine hydrochloride has been associated with peripheral neuritis, evidenced by paresthesia, numbness and tingling, which may be related to an antipyridoxine effect.
The recent publication of the A-HeFt study (7) and the FDA approval of a fixed-dose combination of hydralazine and isosorbide-dinitrate BiDil (8) for use in African-American patients with heart failure mean that clinicians will be faced with the difficult task of initiating and monitoring their African-American patients with heart failure on hydralazine.
We currently are testing to see if hydralazine can reduce symptoms if treatment starts after they begin," he said.
The fixed-dose combination of isosorbide dinitrate and hydralazine is marketed by Arbor Pharmaceuticals under the brand name of BiDil[R].
The update strengthens recommendations on using the combination of hydralazine and isosorbide dinitrate in African American patients, citing clinical trial evidence that this patient population benefits from the addition of this combination to standard therapy with an ACE inhibitor and/or a beta blocker.
In addition, the company launched Hydralazine Hydrochloride, an existing generic, with estimated sales of $23 million in 2008 according to IMS data.
label in 2006 and currently markets 11 products over 50 SKU's, including Ethambutol tablets, Hydralazine tablets, Hydrochlorothiazide tablets, Sulindac tablets, Nimodipine soft gels, Propranolol tablets, Propoxyphene HCl capsules, Meprobamate tablets, Hydroxyzine tablets, Paromomycin capsules and Ropinirole tablets.
Procainamide, hydralazine, isoniazid, and penicillamine are other causative agents.
The most common drugs that can cause lupus are (1) procainamide used for heart problems, (2) hydralazine used for high blood pressure, and (3) dilantin used for seizures.
Patients should be monitored at each visit, and, if any signs and symptoms of SLE develop while the patient is on hydralazine therapy, the drug should be discontinued immediately because complications from the syndrome can be potentially fatal.