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hydroxamic acid

   Also found in: Medical, Wikipedia 0.01 sec.
hydroxamic acid [¦hī‚dräk¦sam·ik ′as·əd]
(organic chemistry)
An organic compound that contains the group ‒C(=O)NHOH.
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Activity of suberoylanilide hydroxamic acid against human breast cancer cells with amplification of her-2.
HER2-directed therapies by Crabb, Simon J.; Chia, Stephen K. / Advances in Breast Cancer
Scientists at the Memorial Sloan-Kettering Cancer Center (MSKCC) in New York City, led by MSKCC president emeritus Paul Marks, have discovered that the HDAC inhibitor suberoylanilide hydroxamic acid (SAHA) causes cancer cells to stop growing and die.
Silent advances by Potera, Carol / Environmental Health Perspectives
and British colleagues added an HDAC inhibitor called suberoylanilide hydroxamic acid to the drinking water of young mice genetically engineered to make mutated huntingtin protein.
Drug limits disease effects in laboratory mice. (Huntington's Advance) by Seppa, N. / Science News
 
 
 
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