Margolis, "N-alkyl urea hydroxamic acids
as a new class of peptide deformylase inhibitors with antibacterial activity" Antimicrobial agents and chemotherapy 46, 9 (2002): 2752-2764.
Table 1: Types of epigenetic drugs: Drugs Class 5-aza-cytidine (azacitidine), Nucleoside DNMTIs 5-aza-2-deoxycytidine (decitabine), 5-fluoro-2-deoxycytidine, Zebularine RG108 Non-Nucleoside DNMTIs MG98 Antisense Oligonucleotides Table 2: HDAC inhibitors: Drugs Class Valproic acid, Aliphatic acids Sodium phenylbutyrate, Pivaloyloxymethyl butyrate, Vorinostat Romidepsin Cyclic peptides Belinostat, Hydroxamic acids
Panobinostat Entinostat, Benzamides Mocetinostat
A number of synthetic compounds including imidazoles, hydroxamic acids
, and phosphazenes are effective urease inhibitors, but limited studies have been conducted on natural products (Ahmad et al.
Important secondary metabolites identified as allelochemicals are phenolics, alkaloids, flavonoids, terpenoids, momilactone, hydroxamic acids
, brassinosteroids, jasmonates, salicylates, glucosinolates, carbohydrates and amino acids (Kruse et al.
are potent allelochemicals of wheat and gene responsible for their expression has been discovered and can be transferred.
are a family of organic acids of general formula RCONHOH and are much weaker acids than the structurally related carboxylic acids (RCOOH), (Nwabueze, 1996).
Colorimetric determination of organic compounds by formation of hydroxamic acids
The chemistry of hydroxamic acids
has received considerable attention [5, 6], and this interest is also connected with a variety of their pharmaceutical and industrial applications [7, 8].
However, Barnes and Putnam (1987) found that barnyardgrass was less sensitive to rye hydroxamic acids
DIBOA (2,4-dihydroxy1,4-benzoxazin-3-one) and BOA (benzoxazolin-2-one) compared to large crabgrass [Digitaria sanguinalis (L.
can be divided into four groups: phenolic acids, hydroxamic acids
are known to be highly active against fungi, bacteria, and some pests (White and Hill 1943, Neilands 1967, Weisburger and Weisburger 1973, Chatterjee 1978, Rather and Hanel 1990, Thackary et al.