hydroxylation reaction

hydroxylation reaction

[hī‚dräk·sə′lā·shən rē‚ak·shən]
(organic chemistry)
One of several types of reactions used to introduce one or more hydroxyl groups into organic compounds; an oxidation reaction as opposed to hydrolysis.
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Joshi, Influence of Preparation Parameters on Characteristics of Zirconia- Pillared Clay Using Ultrasonic Technique and Its Catalytic Performance in Phenol Hydroxylation Reaction, Kor.
25) In the reaction, 1 atom of molecular oxygen is transferred to the substrate and the other one is reduced to water by 1 mole of NADPH, and molecular oxygen is activated for the hydroxylation reaction.
These multiple carbon-carbon double bonds are also capable to be reacted to introduce hydroxyl groups through a hydroxylation reaction.
We now own the IP from the agreement, including the proprietary database of about 500 metabolism measurements used in building our predictions for the hydroxylation reaction caused by a family of enzymes known as Cytochrome P450s, and about 900 compounds used to build our substrate classification (i.
It is shown here that, unlike the complete hydroxylation reaction, the uncoupled decarboxylation reaction involves stoichiometric ascorbate consumption.
The modified oil obtained after the two modification steps was used as a natural hydroxyl source in the polyurethane production and the hydroxylated tung oil (HTO) product of the hydroxylation reaction is just an intermediate product in this work.
In the course of the hydroxylation reaction, the enzyme-bound Fe(II) splits dioxygen into two atoms, being converted itself to Fe(III) or Fe(IV).
Vitamin C is necessary for multiple hydroxylation reactions, including hydroxylation of proline and lysine in collagen synthesis, beta-hydroxybutyric acid in carnitine synthesis, and dopamine-beta-hydroxylase in catecholamine synthesis.
2] The vitamins D2 and D3 are not biologically active, but are converted in vivo to the active form of the D vitamin by two sequential hydroxylation reactions.
These variants were near genes involved in cholesterol synthesis, hydroxylation reactions, and vitamin D transport.
It is biologically inert and has to undergo two hydroxylation reactions to become active in the body.
Two different enzymes power the hydroxylation reactions that make all this possible: prolyl-4-hydroxylase and lysyl-hydroxylase.