hydroxyurea

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hydroxyurea

[‚hī¦dräk·sē·yu̇′rē·ə]

(pharmacology)

HONHCONH₂ Needlelike crystals with a melting point of 133-136°C; used as an antineoplastic agent. Also known as hydroxycarbamide.

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References in periodicals archive ?

The children so identified, are placed on monthly transfusions or daily oral hydroxyurea especially in situations where safe blood is not readily available as a means of stroke prevention.

Stroke in children with sickle cell disorder is preventable -Expert

Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia.

CDC Grand Rounds: Improving the Lives of Persons with Sickle Cell Disease

She had been on hydroxyurea only one year before confirmation of pregnancy and then stopped.

Complications and outcomes of pregnancy in women with sickle cell anaemia--a study conducted in a tertiary care centre in north kerala

Published analytical techniques for the measurement of hydroxyurea in biological fluids include colorimetric spectrophotometry (10,11), HPLC (12-15), and mass spectrometry (MS) (16, 17).

Stable-Isotope Dilution HPLC-Electrospray Ionization Tandem Mass Spectrometry Method for Quantifying Hydroxyurea in Dried Blood Samples

The GDN earlier reported that more than 40 per cent of sufferers being cared for at the Genetic Blood Disease Centre in SMC are now taking hydroxyurea that was first made widely available in Bahrain last year.

Sickle cell drive 'major success'

He was initially well controlled on the standard hydroxyurea treatment.

The search is on: ruxolitinib is linked to aggressive skin cancer

used hydroxyurea, a chemotherapeutic agent which induces Hb F production, at a dose of 10 mg/kg, in their patients assuming that since pathophysiology of Hb SD-Punjab is similar to Hb SS, increasing the level of Hb F might decrease the vaso- occlusive events.

Haemoglobin sickle D disease: A presentation with ischaemic stroke

Hydroxyurea 2 gm every 12 hours was added to rapidly reduce the white blood cell count.

Myeloid neoplasms with t(5;12) and ETV6-ACSL6 gene fusion, potential mimickers of myeloid neoplasm with PDGFRB rearrangement: case report with imatinib therapy and review of the literature

Studies proved the efficacy of hydroxyurea medication in reducing the number of bouts of pain.

Ministry continues to improve sickler patient care

sup][1] Hydroxyurea is another reportedfirst-line agent, and combined medication of hydroxyurea and corticosteroid increases the response rate.

Paraneoplastic Eosinophilia in Clear Cell Renal Cell Carcinoma

has earned a $25 million milestone payment from Novartis, triggered by the EMA's positive opinion for Jakavi (ruxolitinib) for the treatment of adult patients with polycythemia vera (PV) who are resistant to or intolerant of hydroxyurea.

Incyte, Novartis

The "much anticipated" guideline to help primary care and emergency clinicians improve the management of sickle cell disease includes a consensus treatment protocol for implementing hydroxyurea therapy and more detailed guidance regarding longterm transfusion therapy, according to a summary report published in Journal of the American Medical Association.