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Cushing's syndrome
(redirected from hypercortisolism)

   Also found in: Medical, Wikipedia, Hutchinson 0.03 sec.
Cushing's syndrome [′ku̇sh·iŋz ‚sin‚drōm]
(medicine)
A complex of symptoms including facial and truncal obesity, hypertension, edema, and osteoporosis, resulting from oversecretion of adrenocortical hormones.


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For this reason, the disorder is sometimes called hypercortisolism.
Research by Gold and George Chrousos of the National Institute of Child Health and Human Development--a coauthor of the NEJM paper with Gold and Frederic Goodwin, director of the Alcohol, Drug Abuse and Mental Health Administration -- suggests this hypercortisolism is indirectly caused by an overproduction of CRH and therefore by an activation of the stress circuits in the brain and body.
 
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