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Hyperkeratosis
(redirected from hyperkeratotic)

    Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
hyperkeratosis [¦hī·pər·ker·ə′tō·səs]
(medicine)
Hypertrophy of the cornea.
Hypertrophy of the horny layer of the skin.
Hyperkeratosis 

excessive development of the corneous layer of the skin in humans. Hyperkeratosis may be caused by external factors (such as prolonged pressure, friction, or the effects of lubricating oils) or internal factors (endocrine dysfunctions, hypovitaminosis A, occupational intoxication). Hyperkeratosis is manifested by the formation of horny plates, nodes of various sizes, protuberances, and spurs; the skin becomes dry and perspiration decreases. Hyperkeratosis may be accompanied by the formation of painful cracks (on the palms and soles). It may be limited (calluses, warts, keratomas) or diffuse, spread over large areas or the entire skin surface (ichthyosis). Treatment consists in soda or soap baths, vitamin therapy, and medications that dissolve the horny substance.
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The affected skin is covered with a dense crop of pinhead sized hyperkeratotic papules.
The red face--an overview and delineation of the MARSH syndrome by Griffiths, Wad / Clinical Dermatology
The Coria transaction will add several marketed dermatology products to Valeant's portfolio, including the CeraVe(R) Skin Care Line, Cloderm(R) Cream for the treatment of dermatoses, Akne-Mycin(R) and Atralin(TM) for the treatment of acne, and Salex(R) for the treatment of hyperkeratotic skin disorders, as well as Tetrix(TM) Cream for the treatment of hand dermatitis which is expected to be launched later this year.
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Schaller M, Korting HC, Kollmann M, Kind P: The hyperkeratotic variant of porokeratosis Mibelli is a distinct entity: clinical and ultrastructural evidence.
A case of porokeratosis showing different clinical patterns of the ... by Karabudak, Ozalem; Dogan, Bilal; Haholu, Aptullah; Harmanyeri, Yavuz / Archives of the Turkish Dermatology and Venerology
 
 
 
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