hypoadrenalism


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Related to hypoadrenalism: hyperadrenalism

hypoadrenalism

[¦hī·pō·ə′dren·əl‚iz·əm]
(medicine)
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The low dose ACTH stimulation test is less sensitive than the overnight metyrapone test for the diagnosis of secondary hypoadrenalism.
Furthermore, patients might not have true hypoadrenalism even when all four of their salivary cortisol measurements are low.
Overt clinical features of hypoadrenalism develop when 80 to 90% of both adrenal cortices are destroyed.
Infants born to mothers taking substantial oral corticosteroid doses during pregnancy should be monitored for signs of hypoadrenalism.
52-year old Female, irregular cycles and other sx DDX: perimenopause, hypothyroidism, hypoadrenalism, anemia Consider: insulin resistance Evaluate for: breast cancer and osteoporosis risk Female Hormones Serum Saliva 24-Hour Urine Estrone Estrone Estrone Estradiol Estradiol Estradiol Estriol Estrio 1 Estriol Progesterone Progesterone 2-hydroxyestrone 16[alpha]- Commentary: Any of these three methods hydroxyestrone would be acceptable for baseline 2/16a ratio measurements.
The hypoadrenalism in AMN can be sufficiently treated with corticosteroids as in Addison's disease; however, the correction of the hypoadrenal state does not change the progressive course of neurological symptoms.
The original description by Schmidt in 1926 of autoimmune disease affecting more than one endocrine organ concerned a patient with thyroiditis and hypoadrenalism.
No symptoms or signs of hypoadrenalism were observed in keeping with the continued secretion of the active glucocorticoid corticosterone, as with congenital deficiency of 17 alpha hydroxylase.
In the endocrine organs such as the pancreas, thyroid or adrenal glands, (pathologies such as Cushing's hyperadrenalism or Addison's hypoadrenalism can occur.