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Any disease of the brain.



a collective term that designates a noninflammatory organic disease of the brain. Some encephalopathies are innate, resulting from embryopathy. Others are the result of infection, poisoning, trauma, or vascular disease of the brain. There are no specific manifestations. The most common encephalopathies resemble neuroses (asthenia, irritability, insomnia, headaches) or psychoses (narrowed scope of interests, passivity, emotional instability, vulgarity). Symptoms may include memory loss or mental deterioration.

Alcoholic encephalopathies are alcoholic psychoses. They may be acute, as in Wernicke’s encephalopathy (named for the German neuropathologist C. Wernicke, who described the condition in 1881), or chronic, as in Korsakov’s psychosis (named for S. S. Korsakov) and alcoholic pseudoparalysis. Lead encephalopathy is caused by chronic poisoning by lead salts.

Treatment for encephalopathies depends on the cause of the disease.

References in periodicals archive ?
Outcome of term infants using Apgar scores at 10 minutes following hypoxic-ischemic encephalopathy.
Mild hypothermia and the distribution of cerebral lesions in neonates with hypoxic-ischemic encephalopathy.
The clinical courses and cerebral findings of these survivors are similar to those seen with perinatal hypoxic-ischemic encephalopathy (so-called cerebral pal sy).
Coverage begins with human brain development and proceeds through neurological evaluation, hypoxic-ischemic encephalopathy, intracranial hemorrhage, metabolic encephalopathies, disorders of the motor system, intracranial infections, perinatal trauma, intracranial mass lesions, and drugs and the developing nervous system.
In less severe, nonfatal cases, prolonged or severe intrauterine hypoxia may lead to serious neonatal complications such as hypoxic-ischemic encephalopathy (HIE), cerebral palsy, and impaired myocardial function (6-8).
The four-year-old was born with hypoxic-ischemic encephalopathy - a condition which stops oxygen reaching the brain.
The primary neonatal outcome assessed--a composite of death, adverse respiratory events, hypoglycemia, sepsis, seizures, necrotizing enterocolitis, hypoxic-ischemic encephalopathy, the need for CPR or ventilator support, 5-minute Apgar score of 3 or below, neonatal intensive care unit (NICU) admission, or prolonged hospitalization--was significantly less likely to occur as gestational age increased to 39 weeks.