Ichthyosis

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Related to ichthyosis vulgaris: atopic dermatitis

ichthyosis

[‚ik·thē′ō·səs]
(medicine)
A congenital skin disease characterized by dryness and scales, especially on the extensor surfaces of the extremities.

Ichthyosis

 

fish skin disease, xeroderma, a skin disease characterized by sharply increased keratogenesis and retarded keratolysis.

Incidence of ichthyosis is a familial condition in half the cases and hereditary in 25 percent. It appears in early childhood (most often around age three), intensifies at puberty, and lasts throughout life. It is expressed in dryness of the skin and the accumulation of horny masses on the skin’s surface, in the form of scales or of massive horny plates that resemble fish scales. The excretion of oil and perspiration decreases sharply. The affection spreads over the entire skin surface, except at joint folds, axillae, and inguinal folds. On the face and scalp, ichthyosis appears in the form of furfuraceous desquamation. The condition of the skin improves in the summertime as a result of increased excretion of oil and sweat. Ichthyosis is treated with hot baths containing soda or table salt, followed by lubrication of the skin with emollient creams. Cod-liver oil and vitamins may be taken internally (in particular vitamin A). In the summer, prolonged sojourns in the south can be helpful (sea bathing).

I. N. VEDROVA

References in periodicals archive ?
Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema.
About 18 months ago, the gene was in fact sequenced, and this led to the discovery that mutations in it are linked to ichthyosis vulgaris (in homozygous individuals) and atopic dermatitis (in heterozygotes).