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Related to ichthyosis vulgaris: atopic dermatitis


A congenital skin disease characterized by dryness and scales, especially on the extensor surfaces of the extremities.



fish skin disease, xeroderma, a skin disease characterized by sharply increased keratogenesis and retarded keratolysis.

Incidence of ichthyosis is a familial condition in half the cases and hereditary in 25 percent. It appears in early childhood (most often around age three), intensifies at puberty, and lasts throughout life. It is expressed in dryness of the skin and the accumulation of horny masses on the skin’s surface, in the form of scales or of massive horny plates that resemble fish scales. The excretion of oil and perspiration decreases sharply. The affection spreads over the entire skin surface, except at joint folds, axillae, and inguinal folds. On the face and scalp, ichthyosis appears in the form of furfuraceous desquamation. The condition of the skin improves in the summertime as a result of increased excretion of oil and sweat. Ichthyosis is treated with hot baths containing soda or table salt, followed by lubrication of the skin with emollient creams. Cod-liver oil and vitamins may be taken internally (in particular vitamin A). In the summer, prolonged sojourns in the south can be helpful (sea bathing).


References in periodicals archive ?
A study of 100 amaX-hosa children in South Africa with severe AD and ichthyosis vulgaris symptoms revealed no FLG mutations.
Note the normal filaggrin staining (left) in a patient without ichthyosis vulgaris versus the reduction in filaggrin staining (right) in a patient with this disease.
Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema.
Note the normal filaggri staining (left) in a patient without ichthyosis vulgaris versus the reduction in filaggrin staining (right) in a patient with this disease.
Less common mutations in the centrally located filaggrin repeat domain have been linked to ichthyosis vulgaris.
8) There may be a familial association with ichthyosis vulgaris and other disorders of keratinization.
Ammonium lactate cream gives physicians and patients an affordable option in treating skin disorders such as xerosis and ichthyosis vulgaris," said Barrie Levitt, M.
When the work of Sybert's group and others was revisited, (6,7) it became clear that FLG mutations were, in fact, the cause of ichthyosis vulgaris.