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Related to idiosyncrasy: drug idiosyncrasy


Med an abnormal reaction of an individual to specific foods, drugs, or other agents



a painful reaction that appears in certain persons to irritants that do not produce similar phenomena in the majority of others. The basis of idiosyncrasy is either a congenital increased sensitivity of the autonomic nervous system to particular irritants or a reaction that arises in the body as a result of the repeated weak action of certain substances that are incapable of stimulating antibody production in the body.

Idiosyncrasy differs from allergy in that it may develop even after the first contact with an intolerable irritant—for instance, simple chemical compounds that do not have the properties of allergens; such food products as fish, roe, crab, milk, eggs, and strawberries; such medications as amidopyrine, antibiotics, and sulfanilamide preparations; the pollens of certain flowers and plants; the odor of various animals; insect poisons; and such physical factors as sunstroke, chill, or trauma.

Soon after contact with the irritant, headache appears in the individual, and his temperature rises, sometimes accompanied by mental agitation, disruption of the function of the organs of digestion (nausea, vomiting, diarrhea) and respiration (dyspnea, coryza), edema of the skin and mucosa, and urticaria. These phenomena, which are caused by disruptions of blood circulation, increased permeability of the vessels, and spasms of the smooth musculature, usually pass quickly, but sometimes may continue for several days. The reaction does not produce insen-sitivity to the repeated action of the agent. Treatment requires avoidance of further contact with the intolerable irritant and lowering the body’s heightened reactivity.



A peculiarity of constitution that makes an individual react differently from most persons to drugs, diet, treatment, or other situations.
Any special or peculiar characteristic or temperament by which a person differs from other persons.
References in periodicals archive ?
The third section (Chapters 16-18) focuses more on the idiosyncrasy credit model, with special attention to issues of conformity and nonconformity.
In series based on signature shapes including "diamonds," "scissors," and pinched-parallelogram "geminis"--choice examples of each were on view--Zox explored the painterly issues of the day (a systematic approach, the materiality of medium and support) while maintaining a modest idiosyncrasy.
A product of the syncretism between modernity and Mexican idiosyncrasy, the work of Luis Barragan continues to represent an architectural manifesto for universal culture.
Suicide has an aura of idiosyncrasy about it,'' Jamison said.
He has turned a personal idiosyncrasy into his political signature.
Yet, far from marginalizing the work, Scarpa's idiosyncrasy continues to inspire architects who, in their own cultures and contexts, are swimming against the tide of homogenized industrial production which has dominated the twentieth century.
She slogs through a swamp of race, history, trauma, and desire, which is hard enough, then pirouettes along a tightrope between grotesque stereotype and idiosyncrasy, which is even trickier.
2]) residence/media museum in the Napa Valley, due for completion in 2000 - as well as the programmatic idiosyncrasy of most of the examples disqualify them as models, three modest and more generally applicable projects could be profitably replicated: Michael Bell's 900sq ft (83[m.