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idiotype |
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idiotype [′id·ē·ə‚tīp] (immunology) The unique amino acid sequence and corresponding three-dimensional structure of the variable region of an immunoglobulin molecule that determines its antigenic specificity. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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When the researchers looked at the antibodies produced by the hybridomas, they found that 28 percent of the hybridomas from spleen cells and 68 percent of those from lymph nodes produced antibodies carrying the distinctive idiotype of the foreign gene. In an accompanying editorial, Idiotype vaccination in follicular lymphoma: knocking on the doorway to a cure, Dr. justifications have been provided that autologous tumor-derived immunoglobulin idiotype coupled to keyhole limpet hemocyanin may be of significant benefit to those affected by the condition. |
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