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immune response gene

   Also found in: Medical 0.01 sec.
immune response gene [i¦myün ri′späns ‚jēn]
(immunology)
Any of a group of genes in the major histocompatibility complex that determines the degree of immune response. Abbreviated IR gene.


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The sequence of dirucotide is associated with the autoimmune process in MS patients with certain immune response genes (HLA types DR2 and/or DR4); MS patients having these genes represent approximately 70 percent of all MS patients.
The primary end point will be a "statistically and clinically significant increase in the time to progression of the disease as measured by the EDSS in patients with HLA-DR2 and/or HL-DR4 immune response genes.
In particular, an immune response gene variant called MICA-A9 is found in approximately 60% of patients who develop PsA.
 
 
 
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