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immunodeficiency |
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immunodeficiencyDefect in immunity that impairs the body's ability to resist infection. The immune system may fail to function for many reasons. Immune disorders caused by a genetic defect are usually evident early in life. Others can be acquired at any age through infections (e.g., AIDS) or immunosuppression. Aspects of the immune response that may be affected include lymphocytes, other leukocytes, antibodies, and complement. Severe combined immunodeficiency (SCID), which arises from several different genetic defects, disrupts all of these. Depending on the cause, treatment for immunodeficiency may be administration of immunoglobulins, bone-marrow transplant, or therapy for the underlying disease. |
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| The Jeffrey Modell Foundation (JMF) is an organization dedicated to research, physician education, patient support, and public awareness of Primary Immunodeficiency Disease (PI). Retinitis pigmentosa (RP) and common variable immunodeficiency disease (CVID), both debilitating disorders, are genetically and phenotypically heterogenous. Her first pediatrician thought she was reading too much into the boy's sickness, but a new doctor suspected immunodeficiency disease almost immediately and arranged to have the boy tested. |
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immunodeficiency disease
