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immunodeficiency
(redirected from immunodeficient)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.02 sec.

immunodeficiency

Defect in immunity that impairs the body's ability to resist infection. The immune system may fail to function for many reasons. Immune disorders caused by a genetic defect are usually evident early in life. Others can be acquired at any age through infections (e.g., AIDS) or immunosuppression. Aspects of the immune response that may be affected include lymphocytes, other leukocytes, antibodies, and complement. Severe combined immunodeficiency (SCID), which arises from several different genetic defects, disrupts all of these. Depending on the cause, treatment for immunodeficiency may be administration of immunoglobulins, bone-marrow transplant, or therapy for the underlying disease.


immunodeficiency
a deficiency in or breakdown of a person's immune system

immunodeficiency [¦im·yə‚nō·də′fish·ən·sē]
(immunology)
Any defect of antibody function or cell-mediated immunity.


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Patients with defects in caspase-8, for example, are immunodeficient and have recurring infections (39).
These cells also engrafted successfully into Non-obese Diabetic/Severe Combined Immunodeficient (NOD/SCID mice), whereas CD138 positive cells did not engraft.
The scope of the conference includes basic and clinical research on viral oncology, immunology, genetics, epidemiology, pathogenesis, drug discovery, and early diagnosis of malignant diseases in AIDS and other immunodeficient states including organ transplantation.
 
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