immunodiffusion


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Related to immunodiffusion: immunoelectrophoresis, single radial immunodiffusion, Radial immunodiffusion, Double Immunodiffusion

immunodiffusion

[¦im·yə·nō·də′fyü·zhən]
(immunology)
A serological procedure in which antigen and antibody solutions are permitted to diffuse toward each other through a gel matrix; interaction is manifested by a precipitin line for each system.
References in periodicals archive ?
Of the 44 patients, 37 (84%) received a diagnosis by using [greater than or equal to] 1 of the following serologic tests for Coccidioides exposure: complement fixation, immunodiffusion, or tube precipitin.
In the present case, studies for an infectious etiology were negative except the positive serum Coccidioides IgM/ IgG by EIA and immunodiffusion.
In double immunodiffusion test, a white band was observed between the two wells of antigen and antibodies for both the PLE-treated and piperine-treated mice serum because of the antigen-antibody reactions (Fig.
After eliminating the cross-reacting antibody using an immunoadsorbent, a strong precipitin line was observed between the egg protein and the antibody in the double immunodiffusion.
As early as 1949, Orjan Ouchterlony used antibodies as reagents for immunodiffusion methods (26), but the major breakthrough was with the application of RIA, which was developed by Solomon Berson and Rosalyn Yalow and for which Yalow was awarded the Nobel Prize.
The purified toxin was highly specific for antisera raised in rabbits against the purified toxin, as revealed by immunodiffusion and immunoblot assays.
Radial immunodiffusion (RID) [8, 9, 10, 11] is used extensively for the quantitative estimation of antigens.
For example, it can accommodate standard pour, spiral or surface inoculated plates, as well as large bioassay and Single Radial Immunodiffusion (SRD) plates.
Approximately 10 days after each injection, a blood sample was collected, the serum was separated and tested for anti-[alpha]2M antibody activity by immunodiffusion (ID) and immunoelectrophoresis (IEP), prior and after its absorbance to normal rat serum.
The isolates were confirmed as nontoxigenic C diphtheriae by the California State Department of Public Health Microbial Diseases Laboratory (Berkeley, CA), using both PCR and the Elek immunodiffusion test.