epitope

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Related to immunodominant epitope: antigenic determinant, discontinuous epitope

epitope:

see immunityimmunity,
ability of an organism to resist disease by identifying and destroying foreign substances or organisms. Although all animals have some immune capabilities, little is known about nonmammalian immunity.
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epitope

[′ep·ə‚tōp]
(immunology)
The portion of the antigen molecule that determines its capacity to combine with the specific combining site of its corresponding antibody in an antigen-antibody interaction.
References in periodicals archive ?
Mutations that occur within the immunodominant epitopes of hepatitis B surface antigen (HBsAg) allow mutant virus to propagate in the presence of a neutralizing immune response, while wild-type virus is reduced to undetectable levels.
The immune response to p53 in breast cancer patients is directed against immunodominant epitopes unrelated to the mutational hotspot.
Common and immunodominant epitopes among circulating nonavian strains have been identified, and many of the same models and algorithms can be used to make predictions against the pathogenic strains (51).