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immunosuppression

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.03 sec.

immunosuppression

Suppression of immunity with drugs, usually to prevent rejection of an organ transplant. Its aim is to allow the recipient to accept the organ permanently with no unpleasant side effects. In some cases the dosage can be reduced or even stopped without causing rejection. Other uses are in the treatment of certain autoimmune diseases and for prevention of erythroblastosis fetalis. Its main drawback is the increased risk of infection for the duration of treatment and of lymphoma in the case of long-term immunosuppression.


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Recipients also need to take antibiotics to prevent infections caused by the immunosuppression medication.
Flu vaccinations are recommended for people age 65 years and older, children age six months to 23 months, pregnant women and people with heart disease, asthma, and other chronic heart and lung disorders, diabetes, kidney diseases, blood disorders, metabolic and immunosuppression disorders.
Our laboratory recently showed that the presence of Pneumocystis carinii-specific amplicons obtained from swabs of the oral cavities of nonimmunocompromised adult rats (Rattus norvegicus) was predictive of the development of P carinii pneumonia after corticosteroid-induced immunosuppression (3).
 
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