in situ hybridization


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Related to in situ hybridization: Fluorescent in situ hybridization

in situ hybridization

[‚in ‚si·chü ‚hī·brəd·ə·zā·shən]
(cell and molecular biology)
A technique permitting identification of particular deoxyribonucleic acid or ribonucleic acid sequences while these sequences remain in their original location in the cell. A cell or tissue is treated with a fixative and then exposed to a labeled (by radioactivity or fluorescence) single-stranded nucleic acid probe that hybridizes with the targeted nucleic acid sequence, revealing its location on a chromosome band when the hybridized sequence is analyzed microscopically.
References in periodicals archive ?
Validation and workflow optimization of human epidermal growth factor receptor 2 testing using INFORM HER2 dual-color in situ hybridization.
2] Nonstandard abbreviations: HER2, human growth factor receptor 2; IHC, immunohistochemistry; UK NEQAS-ICC, United Kingdom National External Quality Assessment Scheme for Immunocytochemistry; FISH, fluorescence in situ hybridization.
Fluorescence in situ hybridization probes targeting these 14 regions were assembled.
In situ hybridization for EBV showed abundant hybridization of EBER in Reed-Sternberg and Hodgkin cells in all EBV LMP-1-positive cases (Fig.
Development of automated brightfield double in situ hybridization (BDISH) application for HER2 gene and chromosome 17 centromere (CEN17) for breast carcinomas and an assay performance comparison to manual dual color HER2 fluorescence in situ hybridization (FISH).
Evaluation of fluorescence in situ hybridization as an ancillary tool to urine cytology in diagnosing urothelial carcinoma.
Analysis of lymphoepithelioma and lymphoepithelioma-like carcinomas for EpsteinBarr viral genomes by in situ hybridization.
Comparative genomic hybridization (CGH) is a molecular cytogenic technique that enables simultaneous enumeration of every chromosome, in contrast to fluorescent in situ hybridization (FISH), which at present can karyotype only a maximum of nine chromosomes, Leeanda Wilton, Ph.
The international Molecular Cytogenetics market is driven by a number of factors, including the increasing use of molecular cytogenetic tools, such as Fluorescence In Situ Hybridization (FISH) and Array-based Comparative Genomic Hybridization (aCGH) for analyzing complex disease traits, gene mapping, gene discovery, and for improving molecular diagnostics capabilities.
Browse through the TOC ofGlobal In Situ Hybridization Market for an in-depth analysis of the industry trends and segments, with help of various tables and figures.
BOSTON -- In situ hybridization may provide a much faster method of diagnosing dimorphic fungal infections than tissue culturing, Jared J.
On gestational day 16, the researchers examined the brain of one fetus from each litter using gene probes and in situ hybridization to obtain a quantitative measurement of gene activity.
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