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vaccine
(redirected from inactivated vaccine)

    Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.03 sec.

vaccine

Preparation containing either killed or weakened live microorganisms or their toxins, introduced by mouth, by injection, or by nasal spray to stimulate production of antibodies against an infectious agent. This confers immunity to that agent, since the B lymphocytes remain sensitized to it and respond to later infection by producing more antibodies. The first vaccine, against smallpox, was introduced by Edward Jenner in 1798. Vaccines have been developed against diseases caused by bacteria (e.g., typhoid, whooping cough, tuberculosis) and by viruses (e.g., measles, influenza, rabies, poliomyelitis). Effectiveness varies, and a small percentage of people have adverse reactions. Those with immunodeficiency disorders should not receive live vaccines.
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? Mentioned in ? References in periodicals archive
 
An inactivated vaccine that induces not only high levels of neutralizing antibody to surface proteins but also CD8 T-cell response against well-conserved antigens derived from internal viral proteins might provide superior protection in an epidemic or pandemic.
Confronting potential influenza A (H5N1) pandemic with better vaccines by Haque, Azizul; Hober, Didier; Kasper, Lloyd H. / Emerging Infectious Diseases
The product is a ready-to-use, inactivated vaccine that can be used in any cow, bull or calf in any stage of production.
NEW PRODUCTS by Kowalski, Michelle / Farm Journal
This will reduce by approximately one half the expected supply of trivalent inactivated vaccine (flu shot) available in the United States for the 2004-05 influenza season.
What to do about the flu vaccine by San Fernando Valley Business Journal
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