inbred strain


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inbred strain

[′in‚bred ‚strān]
(genetics)
Animal strain that results when individuals that are more closely related to each other than randomly chosen individuals mate together for many generations.
References in periodicals archive ?
Since the convulsions of the EL mouse were first observed and established as epilepsy, the inbred strain has been kept, and data were obtained to elucidate the mechanism of epilepsy and abnormal plasticity.
1) The number of repetitions of some microsatellites differs among individuals or inbred strains and therefore can be used as a marker, allowing researchers to track how specific microsatellite sequences are inherited.
Recombinant inbred (RI) mouse strains: Sets of animal strains derived from the same two parental inbred strains that each carry a specific combination of the parental genes; within each RI strain all animals are genetically identical.
Many studies that might explain this difference have been conducted, comparing these strains and a large panel of recombinant inbred strains derived from them for both biological and behavioral factors.
Little and his colleagues at the Maine center raised money by selling inbred strains of mice to other scientists.
The most commonly used heterogeneous mouse stock was produced by interbreeding eight genetically diverse inbred strains.
DO mice encompass much greater genetic diversity than the classical inbred strains and commercial outbred stocks.
Falls and colleagues (1997) found that a marked FPS response could be detected in the DBA/2J (D2) but not in the C57BL/6J (B6) inbred strain.
Scientists first found evidence for the H-Y antigen when they transplanted skin between members of a highly inbred strain of laboratory mice.
Consequently, all animals within an inbred strain are genetically identical, akin to identical twins.