proband

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Related to index case: index patient, primary case

proband

[′prō‚band]
(genetics)
The clinically affected individual through whom a family is found that can be used to study the genetics of a particular disorder. Also known as propositius.
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Family members of the pediatric index case were evaluated by a pediatric infectious diseases specialist and adult family members were evaluated by an infectious diseases specialist.
The second case in this report had physical contact with the index case when assisting the index case to the bathroom (it lasted for 10 min) and had no history of exposure to live poultry or LPMs before the illness onset.
of index case Nimba Small Ganta 900 July 16 Grand Kru Parluken 2,000 August 4 Grand Cape Mount Jenewonde 800 August 28 Grand Bassa John Logan Town 5,000 September 9 Bomi Dorley-La 301 September 16 Gbarpolu Geleyansiesu 800 September 27 Bong Bomota 397 October 12 Sinoe Government Camp 6,200 October 13 Grand Bassa Quewein 371 October 14 Rivercess Kayah 5,000 October 16 Bong Tayla-ta 500 October 24 Grand Cape Mount Waleaquah 700 November 20 Total no.
A history of a known index case is observed in 71 (27-6%) patients: 57 within the household and 14 amongst social contacts.
Table 1: Biochemical indices in the index case Biochemical indices Index BMD case References range CPK (U/L) 2461.
The Index case: The Index case in this outbreak was a 21 year old female with history of drowsi-ness, high fever and fits for few hours before her admission to the hospital through Emergency.
The objectives of the trial are two-fold: to assess if the vaccine protects the contacts who were vaccinated and if vaccinating the contacts will create a buffer - or ring of protected individuals - around the index case to prevent further spread of the infection.
a--anthropometric parameters: weight and size of the index case.