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infectious mononucleosis |
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infectious mononucleosis an acute infectious disease, caused by Epstein-Barr virus, characterized by fever, sore throat, swollen and painful lymph nodes, and abnormal lymphocytes in the blood Infectious mononucleosis A disease of children and young adults, characterized by fever and enlarged lymph nodes and spleen. EB (Epstein-Barr) herpesvirus is the causative agent. Onset of the disease is slow and nonspecific with variable fever and malaise; later, cervical lymph nodes enlarge, and in about 50% of cases the spleen also becomes enlarged. The disease lasts 4–20 days or longer. Epidemics are common in institutions where young people live. EB virus infections occurring in early childhood are usually asymptomatic. In later childhood and adolescence, the disease more often accompanies infection—although even at these ages inapparent infections are common. See Epstein-Barr virus |
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EBV does cause infectious mononucleosis, hairy leukoplakia, and B-lymphoproliferative neoplasms in immunocompromised persons. A study published in the Annals of Neurology has found that adolescents and young adults who contract infectious mononucleosis (also known as glandular fever) may face a twofold risk of developing multiple sclerosis in later life. But if a person gets an Epstein-Barr infection after the onset of adolescence, the virus can cause infectious mononucleosis. |
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