infiltrate

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infiltrate

1. Pathol any substance that passes into and accumulates within cells, tissues, or organs
2. Pathol a local anaesthetic solution injected into the tissues to cause local anaesthesia

Infiltrate

 

an accumulation in bodily tissues of cellular elements admixed with blood and lymph. Inflammatory and tumorous infiltrates occur most often.

An inflammatory infiltrate consists chiefly of polymorphonuclear leukocytes (suppurative infiltrate), erythrocytes (hemorrhagic infiltrate), lymphoid cells (round cell infiltrate), and histiocytes and plasma cells (histiocyte-plasma cell infiltrate). These infiltrates may be resolved, may liquefy, or may undergo sclerosis and form caverns, abscesses, scars, and so forth.

A tumorous infiltrate consists of tumor cells of different kinds (carcinoma, sarcoma); it is a manifestation of the infiltrating growth of a tumor. When an infiltrate forms, the tissue enlarges, changes color, and becomes harder and sometimes painful. In surgical practice, an infiltrate is an induration that develops in tissues when they become saturated with an anesthetic.

V. V. SEROV

References in periodicals archive ?
Know how to recognise corneal infiltrates and the differential diagnosis.
After the decrease in dosage of maintenance immunosuppression, the persistence on successive TBBs of several perivascular lymphoid infiltrates composed of predominantly small-sized lymphoid cells was interpreted as a sign of mild ACR (grade 2), according to the pulmonary allograft rejection classification.
What: A Muslim FBI undercover agent (Michael Ealy) infiltrates a Los Angeles terrorist sleeper cell.
The number of colonies obtained, as well as features of the source of the clinical sample and the chest radiograph (clearly pathologic) at the time the isolate was obtained, strongly suggest that this microorganism was associated with lung infiltrates and poor prognosis, resulting in the death of the patient.
But at the same time a cadet, played by Leonardo DiCaprio, infiltrates the gang.
007) and the percentage of specimens with pronounced infiltrates of lymphocytes and macrophages in periadnexal areas of the deep dermis (26% to 0%, p = 0.
These inflammatory fibrosclerotic lesions characteristically exhibit a florid proliferation of fibroblasts on a cellular background of mixed inflammatory infiltrates of lymphocytes, plasma cells, and eosinophils.
Histopathologic findings included extensive epidermal and dermal necrosis and acute inflammation at the site of the eschar with focal, transmural, mixed inflammatory cell infiltrates involving dermal blood vessels (Figure 1).
In the tumor stage, localized cutaneous T-cell lymphoma is associated with large reactive lymphoid infiltrates around the periphery of the lymphoma, and repeat biopsies are often necessary to obtain adequate diagnostic tissue.
The brain demonstrated characteristic microglial nodules and perivascular lymphocytic infiltrates (4).
The pars pylorica region of the stomach had multifocal mucosal abscesses and moderate diffuse lymphoplasmacytic and heterophilic infiltrates of the lamina propria.