initiation factor


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initiation factor

[i‚nish·ē′ā·shən ‚fak·tər]
(cell and molecular biology)
Any protein required for the initiation of protein synthesis.
References in periodicals archive ?
Evolutionary relationship between translation initiation factor elF2gamma and selenocysteine-specific elongation factor SELB: change of function in translation factors.
Senesco is a cancer therapeutics company employing its strong proprietary platform in eukaryotic translation initiation Factor 5A (eIF5A) technology to regulate cell death and survival.
Corixa Corporation (Seattle, WA; 206-754-5720), a research-based biotechnology company, announced that the United States Patent and Trademark Office has issued the company three patents granting composition and method claims covering Corixa's proprietary vaccine adjuvant protein known as Leishmania elongation Initiation Factor, or LeIF.
Project title: The eukaryotic translation initiation factor eIF4E: a novel therapeutic target in myeloid leukemia John Crispino, Ph.
A sensitive immunoblotting method for measuring protein synthesis initiation factor levels in lysates of Escherichia coli.
Senesco, a leader in eIF5A technology, is running a clinical study in multiple myeloma with its lead therapeutic candidate SNS01-T, which targets B-cell cancers by selectively inducing apoptosis by modulating eukaryotic translation initiation factor 5A (eIF5A), which is believed to be an important regulator of cell growth and cell death.
eIF4E is an attractive cancer therapeutic target because every function necessary for cancer growth and metastasis is influenced or mediated be a gene product that is regulated by this translation initiation factor.