4,5 A study has shown that for an undisturbed embryonic development, a sufficient number of inner cell mass
The IMO groups' blastocysts had brighter appearance, more prominent inner cell mass
and less irregularities compared with blastocysts produced in SOFaaBSA alone (Figure 1).
Pleuripotent stem cells originate as inner cell mass
within a blastocyst (Blastula).
Once a fertilized egg has gone through several rounds of division, stem cells form a bulge, called the inner cell mass
, inside the early embryo.
After about five days, a blastocyst forms: Cells move to form a thin layer around the edge and a group of small cells, called the inner cell mass
, assembles along one side.
All cells of the early human embryo are totipotent until shortly after the blastocyst stage, including the cells of the inner cell mass
and even the primitive germ-line cells.
Another source of inner ear progenitor cells are embryonic stem cells, which are derived from the inner cell mass
of the mouse blastocyst (figure 3).
Representative slides demonstrated considerable integration of the Y chromosome throughout the inner cell mass
and the trophectoderm (the tissue layer that forms the wall of the early embryo) of the 5-day-old recipient embryos and throughout the completely hatched 6-day-old recipient embryos.
The inner cell mass
of the blastocyst resulting from somatic cell nuclear transfer.
Embryonic stem cells are self-renewing, undifferentiated cells that are extracted from the inner cell mass
of a 5-6 day old embryo or blastocyst.
4) One could theoretically harvest the cells of the morula prior to blastocyst formation; each of these thirty-two cells is capable of producing both placental and embryonic tissue and therefore has totipotentiality while the inner cell mass
of a later embryo has pluripotentiality.
The placenta is primarily derived from embryonic trophoblast cells with additional mesodermal cells derived from the inner cell mass