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integral membrane protein

   Also found in: Dictionary/thesaurus, Medical, Legal, Acronyms, Wikipedia 0.01 sec.
integral membrane protein [¦int·i·grəl ′mem‚brān ‚prō‚tēn]
(cell and molecular biology)
A protein that is firmly anchored in the plasma membrane via interactions between its hydrophobic domains and the membrane phospholipids. Also known as intrinsic protein.
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Integral Molecular, a solution provider for scientific research and drug discovery applications involving integral membrane proteins, has developed a technology, the Lipoparticle, that enables integral membrane protein interactions to be measured using Bio-Rad's label-free, high throughput ProteOn XPR36 Protein Interaction Array System.
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About Integral Molecular: Integral Molecular is a biotechnology company that provides innovative solutions for research and drug discovery applications involving integral membrane proteins.
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The first five chapters examine the production of proteins for structural biology, specifically discussing the use of a dual affinity tag for the production of recombinant protein; the cloning, expression, and purification of yeast proteins in a medium-sized structural genomics group, baculovirus expression of integral membrane proteins, and selenomethionine substitution in bacteria and eukaryotic cells.
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