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integrin

   Also found in: Medical, Wikipedia 0.01 sec.
integrin [in′teg·rən]
(cell molecular)
A heterodimeric transmembrane receptor protein of animal cells that binds to components of the extracellular matrix on the outside of a cell and to the cytoskeleton on the inside of the cell, functionally connecting the cell interior to its exterior; in blood cells, integrins are also involved in cell-cell adhesion.


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The researchers say that, together, these molecules-called integrin and netrin-may be a valuable new target in the efforts to halt cancer's spread via metastasis.
Several changes were observed after collagen glycation: (1) fibroblast shape and distribution (vimentin staining) were modified; (2) extracellular matrix molecules and the dermal-epidermal junction zone seemed to be enhanced (procollagen I and III, collagen IV and VII stainings); (3) stainings for beta1 and alpha6 integrins were also increased in the epidermal cell layer; and (4) collagenase activity was increased.
Syn-Tacks combines two different peptides and stimulates Laminin V, collagen types IV, VII and XVII and Integrin all at once.
 
 
 
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