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integrin |
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integrin [in′teg·rən] (cell molecular) A heterodimeric transmembrane receptor protein of animal cells that binds to components of the extracellular matrix on the outside of a cell and to the cytoskeleton on the inside of the cell, functionally connecting the cell interior to its exterior; in blood cells, integrins are also involved in cell-cell adhesion. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Similarly, basic research on the significance of the integrin molecule led to the development of Tysabri. The drug combats MS by binding to a protein called alpha-4 integrin on the surface of white blood cells, interfering with their entry into the brain. Santa Cruz, CA, USA), or integrin [beta]3 (611141; BD Transduction Laboratories, Franklin Lakes, NJ, USA) or goat antibody against [beta]-actin (sc-1616; Santa Cruz Biotechnology, Inc. |
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