intercalated disc


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intercalated disc

[in′tər·kə‚lād·əd ′disk]
(histology)
A dense region at the junction of cellular units in cardiac muscle.
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Targeted deletion of mXin[alpha] gene, encoding an intercalated disc protein, leads to cardiac hypertrophy (Abstract).
The intercalated discs and the lateral borders were visualised by antibodies against cadherin and type IV collagen (for details see Bruel et al.
Subsequent microscopic analysis of the rabbits' hearts showed the transplanted cells had developed intercalated discs, "a distinctly cardiac feature" that is involved in transferring from cell-to-cell the electrical charge that powers the heartbeat, said investigator Doris Taylor, Ph.