interleukin-10


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interleukin-10

[‚in·tər¦lük ′ten]
(immunology)
An immunoregulatory cytokine produced by a subset of helper T cells as well as by B lymphocytes and some cells of the uterus during pregnancy, it inhibits secretion (and function) of cytokine by macrophages and the second population of helper T cells called Th1. Abbreviated IL-10.
References in periodicals archive ?
Preclinical studies have shown that AM0010, a PEGylated form of recombinant human interleukin-10 (PEG-rHuIL-10), directly activates tumor specific CD8+ killer T lymphocytes.
T-lymphocyte subsets and inflammatory cytokines of interleukin-5 and interleukin-10 expression in human nasal polyp tissue [in Chinese].
Frequency of functional interleukin-10 promoter polymorphism is different between relapse-onset and primary progressive multiple sclerosis.
Interleukin-10 levels are often elevated in serum of adults with Hodgkin's disease and are associated with inferior failure-free survival.
Statistical analyses were used to create a biomarker risk score, which included levels of a number of protein biomarkers, including fibrinogen (a clotting protein), interleukin-10 (associated with the immune system) and C-reactive protein (an inflammatory marker).
Markers of immune health such TNF-[alpha], interferon-gamma, interleukin-10 (IL-10) and IL-8, which would be produced when the host's immune system is challenged, were reduced following consumption of the gluten free diet.
Plasma levels of cytokines tumor necrosis factor alpha (TNF-[alpha]), interleukin-6 (IL-6), interleukin-10 (IL-10) and the expression of prostaglandin [E.
Pharma-Planta project scientists have created interleukin-10 (IL-10) from these tobacco plants at sufficiently high levels for effective extraction and purification.
Italian researchers grew tobacco plants containing genes for interleukin-10, a "cytokine" immune system signalling molecule.
Interleukin-10 inhibition of the progression established collagen induced arthritis.
The immunological status of PKDL patients continues to be characterized but the picture is complex with mixed T cell responses and elevated levels of interleukin-10 (IL-10) and tumour necrosis factor alpha (TNF-[alpha]) (6-9).