interleukin-10


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interleukin-10

[‚in·tər¦lük ′ten]
(immunology)
An immunoregulatory cytokine produced by a subset of helper T cells as well as by B lymphocytes and some cells of the uterus during pregnancy, it inhibits secretion (and function) of cytokine by macrophages and the second population of helper T cells called Th1. Abbreviated IL-10.
References in periodicals archive ?
Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy.
Association of interleukin-10 gene polymorphisms with severe generalized chronic periodontitis.
Maternal serum interleukin-10, interleukin-2 and interleukin-6 in preeclampsia and eclampsia.
T-lymphocyte subsets and inflammatory cytokines of interleukin-5 and interleukin-10 expression in human nasal polyp tissue [in Chinese].
Blood samples were analyzed for serum 2 5-hydroxyvitamin D, the inflammatory markers serum C-reactive protein (CRP), tumor necrosis factor-alpha and interleukin-6 (IL-6), and the anti-inflammatory cytokine interleukin-10 (IL-10).
The researchers, from Brigham and Women's Hospital, and Harvard Stem Cell Institute, and collaborators at MIT and Massachusetts General Hospital, inserted modified strands of messenger RNA into connective tissue stem cells--called mesenchymal stem cells--which stimulated the cells to produce adhesive surface proteins and secrete interleukin-10, an anti-inflammatory molecule.
The researchers, from Brigham and Women's Hospital, and Harvard Stem Cell Institute, and collaborators at MIT and Massachusetts General Hospital, inserted modified strands of messenger RNA into connective tissue stem cells --called mesenchymal stem cells--which stimulated the cells to produce adhesive surface proteins and secrete interleukin-10, an anti-inflammatory molecule.
Interleukin-10 predicts preterm birth in acculturated Hispanics.
Interleukin-10 (IL-10) is a potent pleiotropic cytokine, located on chromosome 1q31-32, consisting of five exons and four introns.
Interleukin-1 beta, interleukin-1 receptor antagonist, interleukin-4 and interleukin-10 gene polymorphisms: relationship to occurrence and severity of rheumatoid arthritis.
5) Rook notes that the observed relationship between abundant Acinetobacter and increased expression of interleukin-10 suggests that Hanski's team has documented a genuine case of immunoregulation by environmental bacteria.