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interleukin-12 |
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interleukin-12 [‚in·tər¦lük·ən ′twelv] (immunology) A heterodimeric cytokine that stimulates nonspecific cytotoxic natural killer-type cells to produce gamma interferon. Abbreviated IL-12. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Furthermore, a Major Histocompatibility Complex (MHC)-class-I-restricted T cell activation ELISPOT assay showed elevated interferon- [gamma], interleukin-2, and interleukin-12 production in HA/SHIV 89. In test-tube studies, the researchers found that this production of interleukin-12 can also arouse the self-reactive immune cells that cause autoimmune problems. In this Phase I open-label study, plasmid DNA encoding a cytokine, interleukin-12 (IL-12), is delivered directly to tumors in patients with malignant melanoma through electroporation using the MedPulser(R) DNA Electroporation System. |
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