interleukin-13


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interleukin-13

[‚in·tər¦lük·ən ′thər‚tēn]
(immunology)
A cytokine produced by activated T lymphocytes that inhibits inflammatory cytokine production induced by bacterial endotoxin and stimulates gamma-interferon production by natural killer cells, enhancing the effect of interleukin-2. Abbreviated IL-13.
References in periodicals archive ?
Eosinophils and CCR3 regulate interleukin-13 transgene-induced pulmonary remodeling.
Lipoxin A4 also discouraged type 2 innate lymphoid cells from promoting inflammation by blocking interleukin-13 secretion.
Interleukin-13 levels in serum from patients with Hodgkin disease and healthy volunteers.
IL-13R alpha2 is believed to be a naturally occurring decoy receptor, capable of binding the cytokine Interleukin-13 (IL-13), but not transmitting a signal to the inside of the cell.
The present Brief Report about biologics such as antibodies, proteins, peptides, antisense and small interference RNA (siRNA) targeting the cytokine interleukin-13 or its receptors IL-13R alpha and IL-4Ralpha provides a competitor analysis of these anti-inflammatory molecules.
Analysis of data from the study found that a clinically-relevant reduction in AAER occurred in a sub-population of patients that had an elevated biomarker associated with increased interleukin-13 (IL-13) activity.
Washington, Mar 23 (ANI): A study conducted by researchers at Duke University has found that changes that occur in the airways of asthma patients are in part caused by the naturally occurring protein interleukin-13 (IL-13) which stimulates invasion of airway cells called fibroblasts.
Dupilumab's "powerful ability" to block interleukin-4 and interleukin-13 pathways of inflammation is "especially exciting because AD is even more Th-2-cell driven in children," said Michael J.
VIENNA -- The success of the interleukin-13 blocker lebrikizumab in the TREBLE trial provides a new avenue in the treatment of moderate to severe atopic dermatitis.
This patent includes specific variations in the inflammatory gene for interleukin-13 (IL-13) and represents part of our expanding coverage of inflammation genes outside the IL-1 gene cluster," added Kenneth S.