interleukin-6


Also found in: Dictionary, Thesaurus, Medical.

interleukin-6

[‚in·tər¦lük·ən ′siks]
(immunology)
A cytokine derived from activated T lymphocytes that has many functions, including induction of B-cell growth; induction of B-cell differentiation and antibody production; induction of differentiation and proliferation of T cells; synergistic induction with IL-3 of hematopoietic cell growth; and induction of hepatocyte secretion of acute-phase inflammatory proteins. Abbreviated IL-6.
References in periodicals archive ?
Study Groups: A total of 75 patients including 46 men and 29 women ranging between 30 - 70 years of age were taken for the estimation of Interleukin-6 in their sera after taking informed consent.
Interleukin-6 (IL-6) is confirmed proinflammatory cytokine which plays central role in the inflammatory response following cerebral hypoxia ischemia (Loddick et al.
Editor's Note: A high level of interleukin-6 was defined as more than 2.
With the help of interleukin-6, angiotensin II causes white blood cells to stick to the endothelial cells lining blood vessels of the retina, which slows blood flow.
Interleukin-6 levels rose significantly during labor in women who did not have fever as well as in those who did, he said.
The researchers found increased production of interleukin-6 in the spleen and lipid peroxides in the liver in the smoking mice.
Although the causes of rheumatoid arthritis are not fully understood, constitutive overproduction of interleukin-6 (IL-6), a multifunctional cytokine that regulates immune response, inflammatory reaction and bone metabolism, is thought to play a major pathological role in RA.
The researchers found that, on average, people who encountered the heart problems had started the study with significantly higher blood concentrations of interleukin-6 and TNF-alpha than did participants who remained healthy.
To investigate whether moderate intake of SSCS initiates proinflammatory response and promotes oxidative damage in healthy, old mice, we tested hepatic lipid peroxide and vitamin E level and splenocyte interleukin-6 (IL-6) production in both nonsmoking and smoking mice.
At the end of the twelve weeks, interleukin-6 and TNF- were decreased among those who received supplemental vitamin B6.
com/research/6ab048/competitor_analysi) has announced the addition of the "Competitor Analysis - Interleukin-6 (IL-6) and Receptor (IL-6R) Antagonists" report to their offering.
The team found increased levels of the cytokines interleukin-6 and interleukin-1-beta in the skeletal and cardiac muscle of mice that received lipopolysaccharide, yet among those that received vitamin E, levels of these cytokines were significantly lower than those of the placebo group.