Neuronal intermediate filaments
and ALS: a new look at an old question.
Desmin intermediate filament
by Nova link polymer detection system was used, according to kit instructions.
As such, dystrophin constitutes a major scaffolding protein of normal muscle which links cytoskeletal actin, microtubules and intermediate filaments
to the extracellular matrix.
8, Cell Marque, Rocklin, CA, USA) used and reacted with intermediate filament
of cytoplasm and cell membrane.
Globoside colocalized intracellularly with intermediate filaments
in a number of cell types: with vimentin in human and mouse fibroblasts, with desmin in smooth muscle cells, with keratin in keratinocytes, and with glial fibrillary acidic protein in glial cells.
expression in mesotheliomas: Leimyoid mesotheliomas are not uncommon.
Keratins that form the intermediate filaments
are expressed exclusively in the epithelial cells regardless of the germ layer origin of these cells.
Tumor cells usually contain intermediate filaments
, have cell junctions, and may contain glycogen, dense core granules, and neurotubles.
Neoplastic cells were positive for vimentin and negative for desmin and actin and showed ultrastructural features (dilated stacks of rough endoplasmic reticulum, intermediate filaments
, rare collagen secretion granules, lack of external lamina) typical of fibroblasts.
REVIEW OF INTERMEDIATE FILAMENTS
, WITH SPECIAL REFERENCE TO CYTOKERATINS.
(IFs) participate in key mechanical functions and play a role in preventing excess large cell stretch.
It consists mainly of intermediate filaments
called lamins and microfilaments cal led act ins and DNA topoisomeraseII (Fig.