Embryonic form of smooth muscle myosin heavy chain (SMemb/MHC-B) in gastrointestinal stromal tumor and interstitial cells
In vitro effects of Askarel on the NADPH-P450 reductase activity in postmitochondrial fractions of interstitial cells
of normal adult rats.
Immunolocalization of gap junction protein Connexin 43 in the interstitial cells
of Cajal in normal and Hirschsprung's disease bowel.
Changes in interstitial cells
of Cajal with age in the human stomach and colon.
Generation of slow wave activity in gastric smooth muscle cells is thought to originate from specialized intramuscular interstitial cells
of Cajal) which evoke electrical depolarization in a rhythmic manner.
1) We previously described a benign stromal tumor of the gallbladder with a phenotype of interstitial cells
It is proposed that the origin of GISTs is from the interstitial cells
of Cajal (ICC) given their CD117 and CD34 expression and histologic similarities to this cell.
Histologically, it is classified into neuropathies, mesenchymopathies and myopathies, according to the predominant involvement of enteric neurons, interstitial cells
of Cajal or smooth-muscle cells, respectively.
Optimal CD117 immunostains should highlight normal interstitial cells
of Cajal and mast cells, whereas smooth muscle cells and fibroblasts should exhibit completely negative findings.
The interstitial cells
of Cajal (ICC) are mesenchymal cells arranged in a characteristic manner in close relation to the nerves and smooth muscle cells in the outer muscular coat of the GI tract4.
Serotonin takes part in biochemical interactions that lead to increased production of a key signaling molecule called TBF-beta-1, which in turn stimulates the aortic valve interstitial cells
to produce an abnormal extracellular matrix, comparable to that associated with fen-phen heart valve disease, according to Dr.
2,3] CD34-positive dendritic interstitial cells
(DICs) and myofibroblasts are two of the stromal cells that appear to be involved with regulation of tumor growth.