Tissue Fluid

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Tissue Fluid


(also called interstitial fluid), the fluid in the intercellular and pericellular areas of tissues and organs in animals and man. Tissue fluid bathes all tissue elements and, together with the blood and lymph, constitutes the body’s internal medium. The cells absorb necessary nutrients from the tissue fluid and discharge metabolic products into it.

The chemical composition and the physical and biological properties of tissue fluid differ in the various organs and correspond to the organs’ morphological and functional characteristics. Tissue fluid is similar to blood plasma, but contains less protein (about 1.5 g per 100 ml) and different proportions of electrolytes, enzymes, and metabolites. The composition and properties of tissue fluid have a specific homeostasis, which protects organ and tissue cells from the effects of changes in blood composition.

Nutrients essential for the tissues enter the tissue fluid from the blood, and metabolites are removed from the tissue fluid through the histohematic connective tissue barrier. When the tissue fluid flows from the organs into the lymphatics, it becomes lymph. The volume of tissue fluid in a rabbit amounts to 23–25 percent of the body mass; in man it amounts to 23–29 percent, with an average of 26.5 percent. Many histologists regard as tissue fluids the cerebrospinal fluid, the pericardial fluid, the fluid of the anterior chamber of the eye, and the fluid of the pleural cavity.

References in periodicals archive ?
Aliquots (1 g/L) of the interstitial fluid were preincubated at 37 [degrees]C for 15 min with 10 mmol/L EDTA for an inhibition test.
If the patient's relative blood volume remains unchanged over the 3 consecutive haemodialysis sessions, that is, the relative blood volume graph is greater than 95% at the end of each dialysis, then the patient still has a lot of interstitial fluid on board, hence DW should be slowly reduced.
3 [micro]l/min, the concentration of metabolites recovered represents approximately 70% of the tree concentration in the interstitial fluid.
Interstitial fluid is taken across the capillary wall by the Donnan effect of plasma proteins.
Time-dependent properties of articular cartilage are related to the interstitial fluid flow and exudation.
It results from an increase in interstitial fluid volume due to an imbalance in the filtration system between the capillary and interstitial spaces.
Chronic leg edema is defined as palpable swelling caused by an increase in interstitial fluid volume lasting at least 72 hours.
This introduction for both undergraduate and graduate students as well as nonspecialist professionals focuses on basic models and computational strategies for fluidized dry particulate flows in which there is no significant interstitial fluid but also covers some fully coupled fluid-particle systems.
Oral fluid-based HIV tests sample oral mucosal transduate (OMT), an interstitial fluid from the capillaries of the gingival gum margin (8,9).
Nonetheless, some fluid must be retained and the composition of the layer immediately below the thin surface layer is selected to be capable of withdrawing the interstitial fluid therefrom.
Recommended Usage: A subcutaneous sensor reads glucose levels in the interstitial fluid between fat and muscle layers for up to 3 days.

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