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1. Pathol any substance that passes into and accumulates within cells, tissues, or organs
2. Pathol a local anaesthetic solution injected into the tissues to cause local anaesthesia



an accumulation in bodily tissues of cellular elements admixed with blood and lymph. Inflammatory and tumorous infiltrates occur most often.

An inflammatory infiltrate consists chiefly of polymorphonuclear leukocytes (suppurative infiltrate), erythrocytes (hemorrhagic infiltrate), lymphoid cells (round cell infiltrate), and histiocytes and plasma cells (histiocyte-plasma cell infiltrate). These infiltrates may be resolved, may liquefy, or may undergo sclerosis and form caverns, abscesses, scars, and so forth.

A tumorous infiltrate consists of tumor cells of different kinds (carcinoma, sarcoma); it is a manifestation of the infiltrating growth of a tumor. When an infiltrate forms, the tissue enlarges, changes color, and becomes harder and sometimes painful. In surgical practice, an infiltrate is an induration that develops in tissues when they become saturated with an anesthetic.


References in periodicals archive ?
Statistically, this is the most common diagnosis proven on biopsy in an older population with chronic interstitial infiltrates.
However, the interstitial infiltrate in hypersensitivity pneumonitis is patchy and less dense, with a peribronchiolar distribution.
3] and her chest X-ray showed interstitial infiltrates with fine nodularity more pronounced in the right lower zone than on the left (Fig.
The other, more common form, seen with higher doses of the medication (400 mg) has an insidious onset and occurs after 2 or more months of therapy with progressive nonproductive cough, dyspnea, weight loss, low-grade fever and interstitial infiltrates.
Pulse oximetry measurements were normal to mildly reduced on admission, but chest x-rays uniformly showed evidence of consolidation and interstitial infiltrates, consistent with atypical pneumonia.
Chest radiography revealed bilateral interstitial infiltrates.
Chest X-ray showed diffuse pulmonary interstitial infiltrates (Figure 1A).
Thoracic radiographs showed mild left atrial enlargement and mild pulmonary interstitial infiltrates.
Chest radiographs often show bilateral interstitial infiltrates with pericardial or pleural effusions.

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