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injection |
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injection, introduction of a fluid into the body, usually by means of a needle and syringe. The material injected may be a test substance (as in determining allergic sensitivity or immunity to a disease), an anesthetic, a therapeutic drug, a nutrient (in cases where intravenous feeding is necessary), blood, or blood plasma (see blood transfusion blood transfusion, transfer of blood from one person to another, or from one animal to another of the same species. Transfusions are performed to replace a substantial loss of blood and as supportive treatment in certain diseases and blood disorders. ..... Click the link for more information. ). An intracutaneous injection is the introduction of a small amount of fluid between the skin layers. A subcutaneous injection is directed to the tissues under the skin. When quicker absorption of a drug is required, an intramuscular injection may be used; even more rapid action is obtained by injection into a vein (intravenous). In certain emergencies involving the heart, such as cardiac arrest, an intracardiac injection can penetrate directly into a chamber of the musculature of the heart. Anesthetics are sometimes injected into the spine. In an injection by means of a jet injector gun, fluid penetrates through the skin by means of air pressure and there is no visible puncture mark. Micro-injections can be made into fetuses, even individual cells, with tiny capillary injectors.
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| 8 administered by intrathecal injection can provide nearly complete pain relief. The goal of the study is to demonstrate the maximum tolerated dose of Spartaject(TM) busulfan in this setting, to characterize the pharmacokinetics of busulfan in the CSF and blood after intrathecal injection, and to assess the response of the patients' neoplastic meningitis to therapy with Spartaject(TM) busulfan. |
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